MCHR1antagonist 1 is a selective antagonist ofmelanin concentrating hormone-1 (MCH1) receptor, with aK_bof 1 nM and aK_iof 4 nM at human MCH1, and may be used to reduce the body mass.

Kb: 1 nM (Human MCH1)^[1]
Ki: 4 nM (Human MCH1)^[1]

MCHR1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with K_is of >50000 nM^[1].

557.59

C₂₈H₃₃F₂N₅O₅

391610-37-0

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.