Arecoline hydrochloride, a naturally occurring psychoactive alkaloid, is a partial agonist ofnicotinicandmuscarinic acetylcholine receptor. Arecoline hydrochloride exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrochloride also can induce oxidative stress^[1][2][3][4].

nAChR/mAChR^[3]

Arecoline hydrochloride induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Arecoline hydrochloride-induced epithelial cell death at higher concentrations is caused by oxidative trauma without eliciting apoptosis. Arecoline hydrochloride upregulates the expression of the following stress-responsive genes: hemeoxygenase-1; ferritin light chain; glucose-6-phosphate dehydrogenase; glutamatecysteine ligase catalytic subunit; and glutathione reductase^[1].

191.66

C₈H₁₄ClNO₂

61-94-9

盐酸槟榔碱；槟榔碱盐酸盐

• Alkaloids
• Other Alkaloids

• Plants
• Palmae
• Areca catechuL.

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.