Ipratropium-d3 bromide (Sch 1000-d3) is the deuterium labeled Ipratropium bromide. Ipratropium bromide (Sch 1000) is amuscarinic receptorantagonist, with bindingIC₅₀values of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

415.38

C₂₀H₂₇D₃BrNO₃

异丙托溴铵 d3 (溴盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.