CAS NO: | 1235-82-1 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Biperiden (KL 373) hydrochloride is a non-selectivemuscarinic receptorantagonist that competitively binds toM1muscarinic receptors, thereby inhibitingacetylcholineand enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Biperiden hydrochloride (29.6 μg/ml, 72 hours) can significantly induce apoptosis and inhibit proliferation at high doses in human pancreatic ductal adenocarcinoma cells[1]. Cell Proliferation Assay[1]
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体内研究 (In Vivo) | Biperiden hydrochloride (intraperitoneal injection, 10 mg/kg, everyday, 3 weeks) reduces tumor size by 83% in subcutaneous xenograft mouse using Panc-1 human pancreatic ductal adenocarcinoma cells[1].
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Clinical Trial | |||||||||||||||||
分子量 | 347.92 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C21H30ClNO | ||||||||||||||||
CAS 号 | 1235-82-1 | ||||||||||||||||
中文名称 | 盐酸比哌立登;双环哌丙醇盐酸盐 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 20 mg/mL(57.48 mM;Need ultrasonic) H2O : 5 mg/mL(14.37 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |