Sphingosine-1-phosphate-d7 (S1P-d7) is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist ofS1P_1-5receptorsand a ligand of GPR3,GPR6and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca²⁺as an extracellular ligand for G protein-coupled receptors^[1]. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membranephospholipids^[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

386.51

C₁₈H₃₁D₇NO₅P

2260670-15-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.