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L-DOPA sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-DOPA sodium图片
CAS NO:63302-01-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Levodopa sodium
3,4-Dihydroxyphenylalanine sodium
产品介绍
L-DOPA (Levodopa) sodium 是一种具有口服活性的神经递质多巴胺的代谢前体。L-DOPA sodium 可以透过血脑屏障,并在大脑中转化为多巴胺。L-DOPA sodium 具有抗痛觉过敏作用,可用于帕金森氏病的研究。
生物活性

L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA sodium can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA sodium has anti-allodynic effects, and can be used for Parkinson's disease research[1][2][3].

IC50& Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

L-DOPA sodium (20 mg/kg; orally) reduces Rotenone-induced motor dysfunction[3].
L-DOPA sodium (0-100 mg/kg; orally) reverses tactile, cold and heat allodynia in neuropathic rat without any side effect in sprague-Dawley rats[4].

Animal Model:C57BL/6J mice (7-week-old)[3]
Dosage:20 mg/kg
Administration:Orally
Result:Reduced Rotenone-induced motor dysfunction.
Animal Model:Sprague-Dawley rats[4]
Dosage:10, 30, 50, 70, and 100 mg/kg
Administration:Orally
Result:Reverses tactile, cold and heat allodynia in neuropathic rat without any side effect.
Clinical Trial
分子量

219.17

Formula

C9H10NNaO4

CAS 号

63302-01-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.