CAS NO: | 104632-25-9 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrantdopamine D2-type receptoragonist, withKis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3and D4receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS)[1][2][3]. | ||||||||||||||||
体外研究 (In Vitro) | Pramipexole shows a low binding affinity for D1-type receptor, with an IC50 of >50,000 nM[1]. | ||||||||||||||||
体内研究 (In Vivo) | Pramipexole dihydrochloride (0.25-1 mg/kg; i.p.) significantly reduces the infarction volume in animals[5].
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Clinical Trial | |||||||||||||||||
分子量 | 284.25 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C10H19Cl2N3S | ||||||||||||||||
CAS 号 | 104632-25-9 | ||||||||||||||||
中文名称 | 盐酸普拉克索;盐酸米拉帕 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : ≥ 50 mg/mL(175.90 mM) *"≥" means soluble, but saturation unknown. 配制储备液
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