TopoisomeraseII inhibitor 9 (Compound 19b) is aTopo IIinhibitor with anIC₅₀of 0.97 μM.TopoisomeraseII inhibitor 9 is also a classical DNA-intercalator with anIC₅₀of 43.51 μM.TopoisomeraseII inhibitor 9 arrests the cell cycle at the G2/M phase and inducesapoptosisin Hep G‐2 cells^[1].

Topoisomerase II inhibitor 9 (Compound 19b) shows antiproliferative activity with IC₅₀values of 0.50 ± 0.1, 0.75 ± 0.1 and 2.91 ± 0.1 μM against Hep G‐2, Hep‐2 and Caco‐2 cells, respectively^[1].

491.55

C₂₂H₁₇N₇O₃S₂

2413901-61-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.