PluriSIn #2 is a selective transcriptional inhibitor oftopoisomeraseII α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs)^[1].

PluriSIn #2 (20 μM; 12 hours) treatment reduces TOP2A expression at the protein level^[1].
A 24h exposure of PluriSIn #2 (20 μM) is sufficient to induce massive cell death in hPSCs, but doesn’t affect the viability of various other cell types derived from them^[1].

249.20

Solid

C₁₁H₈FN₃O₃

56563-17-8

Room temperature in continental US; may vary elsewhere.

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

DMSO : 5 mg/mL(20.06 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light, stored under nitrogen)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。