Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selectivePPARγagonist with high affinity binding to thePPARγligand-binding domain withEC₅₀of 0.93 and 0.99 μM for human and mousePPARγ, respectively^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

360.46

C₁₉H₁₆D₄N₂O₃S

1134163-31-7

吡格列酮 d4 (alkyl)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.