CAS NO: | 420826-65-9 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | BAY-0069 is a potent and selectivePPARγinverse agonist with anIC50value of 6.3 nM and 24 nM for humanPPARγand mousePPARγ. BAY-0069 can be used to researchcancer[1]. | ||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | BAY-0069 inhibits CYP2C8 with an IC50of 4.3 μM[1]. Cell Proliferation Assay[1]
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体内研究 (In Vivo) | BAY-0069 (1 μM; 1 h) exhibits excellent microsomal stability with CLb,hmicof 0.47 L/h/kg in human liver microsomes and CLb,rhepof 3.9 L/h/kg in rat liver hepatocytes[1].
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分子量 | 466.28 | ||||||||||||
Formula | C22H16BrN3O4 | ||||||||||||
CAS 号 | 420826-65-9 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |