您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Cefepime Dihydrochloride Monohydrate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cefepime Dihydrochloride Monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cefepime Dihydrochloride Monohydrate图片
CAS NO:123171-59-5
包装与价格:
包装价格(元)
500mg电议
1g电议
5g电议

产品介绍
头孢吡肟二盐酸盐一水合物是一种广谱头孢菌素,具有增强的对革兰氏阳性和革兰氏阴性细菌的覆盖率。
Cas No.123171-59-5
别名头孢吡肟盐酸盐
化学名(1S,8R)-8-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-4-((1-methylpyrrolidin-1-ium-1-yl)methyl)-7-oxo-2-thiabicyclo[4.2.0]oct-4-ene-5-carboxylate dihydrochloride hydrate
Canonical SMILESNC1=NC(/C(C(N[C@H]2[C@]3([H])C(C(C([O-])=O)=C(C[N+]4(C)CCCC4)CS3)C2=O)=O)=N/OC)=CS1.Cl.Cl.O
分子式C20H29Cl2N5O6S2
分子量570.5
溶解度≥ 57.1mg/mL in DMSO
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria[1].

Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics[1].

Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin and skin structure infections. Cefepime is generally well tolerated[2].

References:
[1]. Neu, H.C., Safety of cefepime: a new extended-spectrum parenteral cephalosporin. Am J Med, 1996. 100(6A): p. 68S-75S.
[2]. Wynd, M.A. and J.A. Paladino, Cefepime: a fourth-generation parenteral cephalosporin. Ann Pharmacother, 1996. 30(12): p. 1414-24.