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Chlorhexidine digluconate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Chlorhexidine digluconate图片
CAS NO:18472-51-0
包装:50mg
市场价:525元

产品介绍
氯己定二葡萄糖酸盐是一种对多种革兰氏阴性和革兰氏阳性微生物有效的防腐剂。
Cas No.18472-51-0
别名氯己定二葡糖酸盐
Canonical SMILESClC1=CC=C(NC(NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N)=N)C=C1.OC[C@](O)([H])[C@](O)([H])[C@@](O)([H])[C@](O)([H])C(O)=O.OC[C@](O)([H])[C@](O)([H])[C@@](O)([H])[C@](O)([H])C(O)=O
分子式C34H54Cl2N10O14
分子量897.76
溶解度≥ 36.4mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Chlorhexidine digluconate is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine digluconate is a chemical antiseptic. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought. It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine digluconate is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions [1, 2].

References:
[1]. Jenkins, S., M. Addy, and W. Wade, The mechanism of action of chlorhexidine. A study of plaque growth on enamel inserts in vivo. J Clin Periodontol, 1988. 15(7): p. 415-24.
[2]. Maki, D.G., M. Ringer, and C.J. Alvarado, Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet, 1991. 338(8763): p. 339-43.