| CAS NO: | 191114-48-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 191114-48-4 |
| 别名 | 泰利霉素; HMR3647; RU66647 |
| Canonical SMILES | CC[C@](O1)([H])[C@@]2([C@](N(C(O2)=O)CCCCN(C=N3)C=C3C4=CN=CC=C4)([H])[C@@](C([C@](C[C@]([C@@](O[C@@]5([H])[C@@](O)([H])[C@](N(C)C)([H])C[C@@](O5)([H])C)([H])[C@@](C([C@@](C1=O)([H])C)=O)([H])C)(OC)C)([H])C)=O)([H])C)C |
| 分子式 | C43H65N5O10 |
| 分子量 | 812.0 |
| 溶解度 | ≥ 21.05mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Telithromycin(HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Target: AntibacterialTelithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. Telithromycin has over 10 times higher affinity to the subunit 50S than erythromycin. In addition, telithromycin strongly bind simultaneously to two domains of 23S RNA of the 50 S ribosomal subunit, where older macrolides bind strongly only to one domain and weakly to the second domain. Telithromycin can also inhibit the formation of ribosomal subunits 50S and 30S. From Wikipedia. References: |
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