Cyclapolin 9 is a potent, selective and ATP-competitivepolo-like kinase1 (PLK1)inhibitor with anIC₅₀of 500 nM. Cyclapolin 9 is inactive against other kinases^[1][2].

Cyclapolin 9 (3 μM) reduces electric field stimulation (EFS)-induced contractions of prostate strips. The α1-adrenergic smooth muscle contraction in the human prostate can be inhibited by Cyclapolin 9^[1].

307.21

Solid

C₉H₄F₃N₃O₄S

40533-25-3

Room temperature in continental US; may vary elsewhere.

DMSO : 55 mg/mL(179.03 mM;Need ultrasonic)

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