Ajoene, a garlic-derived compound, is anantithromboticandantifungalagent. Ajoene inhibits proliferation and inducesapoptosisof human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities^[1][2].

Ajoene shows cytotoxicity with IC₅₀s in the 7-41 uM range for B16/BL6, HT-29, A549, MDA-MB231, PANC-1, and SKBR-3 cells^[1].

Ajoene (25 μg/g body weight of Ajoene in 100 mL Intralipid; i.p.; every other day from the day of inoculation up to day 28) inhibits both primary tumor growth^[1].
Ajoene (25, 15 or 5 μg/g body weight of Ajoene in 100 μL Intralipid; i.p; every other day over 4 weeks) inhibits strongly metastasis to lung in the B16/BL6 melanoma tumor model in C57BL/6 mice^[1].

234.40

Liquid

C₉H₁₄OS₃

92285-01-3

• Others

• Plants
• Liliaceae
• A．SativamL. var．Viviparum Regel

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years