CAS NO: | 1382722-47-5 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA)MMP-2inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity ofMMP-13,MMP-1andMMP-9withIC50s of 1.8 μM,10 μM, and 13 μM, respectively[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | MMPI-1154 (1-100 μM) inhibits MMP-2 enzyme isolated from rat heart in vitro, and 100% inhibition appears at the concentraction 100 μM[1].MMPI-1154 (1 μM) shows significant cardio-cytoprotecion, significantly decreases infarct size in an ex vivo model for acute myocardial infarction[1]. | ||||||||||||||||
分子量 | 445.49 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C26H24FN3O3 | ||||||||||||||||
CAS 号 | 1382722-47-5 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 83.33 mg/mL(187.05 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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