Enocitabine is a nucleoside analog, and is a potentDNA replicationinhibitor, and a DNA chain terminator. Enocitabine inhibits the replication ofhuman cytomegalovirus. Enocitabine has antileukemic and antiviral activities^[1][2][3].

DNA replication^[1]; CMV^[3]

Enocitabine is resistant to deamination because Enocitabine bears a highly lipophilic group at the 4-amino position of the cytosine moiety of cytarabine^[1].
The combined effects of Pirarubicin and Enocitabine on HeLa S3 human uterine cervix carcinoma and K562 human myelocytic leukemia cells are determined by enhancement of their cytotoxic activities. Enocitabine or etoposide shows synergistic effects on HeLa S3 and K562 cells^[2].
In the presence of Enocitabine, triphosphate forms of the nucleoside analogs are detected in the human cytomegalovirus (HCMV)-infected cells, and synthesis of HCMV DNA is strongly suppressed^[3].

565.78

Solid

C₃₁H₅₅N₃O₆

55726-47-1

依诺他滨；依诺他宾

Room temperature in continental US; may vary elsewhere.

DMSO : 2 mg/mL(3.53 mM;ultrasonic and warming and heat to 60℃)

H₂O :< 0.1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble)

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储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。