包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | XY153 (compound 8l) is a BD2-selectiveBETinhibitor and selectively binds toBRD4BD2. XY153 binds toBRD4BD2,BRD3BD2 andBRD2BD2 withIC50s of 0.79, 5.31 and 5.09 nM, respectively. XY153 shows potent antiproliferative activity against multiple tumor cell lines. XY153 can be used for the research of acute myeloid leukemia (AML) andcancer[1]. | ||||||||
IC50& Target | IC50: 0.79 nM (BRD4 BD2), 5.31 nM (BRD3 BD2), 5.09 nM (BRD2 BD2)[1] | ||||||||
体外研究 (In Vitro) | XY153 shows strong antiproliferative activities for specific cancer cell lines but with a better safety profile against a normal lung fibroblast cell line[1]. Cell Viability Assay[1]
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分子量 | 555.64 | ||||||||
Formula | C33H34FN3O4 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |