DVR-01 is aHBVinhibitor withEC₅₀values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistantHBVmutants withEC₅₀s of 2.403-3.273 μM. DVR-01 can be used for the research of HBVinfectionand related diseases^[1].

DVR-01 (0-10 μM; 4 d) inhibits HBV in human hepatoma cells with EC₅₀values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively^[1].
DVR-01 (0.156-10 μM; 2 d) selectively disrupts the pgRNA encapsidation by HBV^[1].
DVR-01 (3 d) shows antiviral activity against hepadnaviruses in human hepatoma cells with EC₅₀s of 2.899, ＞10 and ＞25 μM for HBV, WHV and DHBV, respectively^[1].
DVR-01 (0.0097-10 μM; 2 d) shows antiviral activity against drug-resistant HBV mutants with EC₅₀s of 2.899, 3.273, 3.180, 2.752, 2.567 and 2.403 μM for wt, rtL180 M/rtM204V, rtA181V, rtN236T, rtM204I and rtL180 M/rtM204V/rtT184G/rtS202I, respectively^[1].

406.93

C₂₀H₂₃ClN₂O₃S

330461-34-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.