CAS NO: | 652153-01-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Zanolimumab (Anti-HumanCD4Recombinant Antibody) is a fully human monoclonal antibody targetsCD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma[1]. |
体外研究 (In Vitro) | Zanolimumab (10 and 100 ng/mL) shows strong killing of the CD4+T cells with a better effect to CD45RO+subset than the CD45RA+subset[1].Zanolimumab (1-10000 ng/mL) Fc and dose-dependently down-regulates the level of CD4 from purified primary CD4+T cells and SUP-T1 T cells[1].Zanolimumab (1-10000 ng/mL) potently inhibits of TCR-stimulated T-cell proliferation both in tetanus toxin induced and anti-CD3 induced T-cell proliferation[1].Zanolimumab (0-30 min) inhibits TCR signal transduction[1]. |
分子量 | 147 (kDa) |
CAS 号 | 652153-01-0 |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |