包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | LSD1/2-IN-3 is a selective inhibitor oflysine-specific demethylase 1(LSD1), with aKivalue of 11 nM instead of 7 μM forLSD2. There is aberrant expression ofLSD1incancer stem cells, LSD1/2-IN-1 inhibitsLSD1cell proliferation[1]. |
IC50& Target | Ki: 11 nM (LSD1); 7 μM (LSD2)[1] |
体外研究 (In Vitro) | LSD1/2-IN-3 (compound 8c) inhibits proliferation of the T-cell acute lymphoblastic leukemia (T-ALL) with IC50s of 25 μM (CCRF-CEM) and 27 μM (Jurkat), respectively, without inhibiting the human normal fibroblast cell line WI-38[1]. |
分子量 | 248.07 |
Formula | C9H8BrF2N |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |