CAS NO: | 2393983-76-9 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PD-1/PD-L1-IN 6 (compound A13) is a potentPD-1/PD-L1interaction inhibitor, with anIC50of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model[1]. |
IC50& Target | IC50: 132.8 ± 6.9 nM (PD-1/PD-L1 interaction) |
分子量 | 402.49 |
Formula | C25H26N2O3 |
CAS 号 | 2393983-76-9 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |