包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PD-1/PD-L1-IN-27 is a potentPD-1/PD-L1inhibitor with anIC50value of 134 nM. PD-1/PD-L1-IN-27 shows antitumor effects with low T cell cytotoxicity. PD-1/PD-L1-IN-27 has the ability to activate CD8+T cells and reduces T cell exhaustion[1]. | ||||||||
IC50& Target | IC50: 134 nM (PD-1/PD-L1)[1] | ||||||||
体外研究 (In Vitro) | PD-1/PD-L1-IN-27 (compound MZ58) (2.5, 5, 10, 50 μM; 48 h) shows antitumor effects with low T cell cytotoxicity[1]. Cell Proliferation Assay[1]
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体内研究 (In Vivo) | PD-1/PD-L1-IN-27 (10, 25 mg/kg; i.g.) shows antitumor effecct[1].
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分子量 | 673.75 | ||||||||
Formula | C44H35NO6 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |