包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PTP1B-IN-20 is a selective inhibitor ofprotein tyrosinephosphatase1B(PTP1B;IC50=1.05 μM) over the highly homologousT-cell protein tyrosinephosphatase(TCPTP;IC50=78.0 μM), which is a key target for type 2 diabetes inhibition[1]. |
IC50& Target | IC50: 1.05 μM (PTP1B); 78.0 μM (TCPTP)[1] |
体外研究 (In Vitro) | PTP1B-IN-20 (compound 4) (0-100 μM; 15 min; 37 ℃) with 5,6-dihydroxyl groups is more potent than the positive control Na3VO4(IC50= 2.94 μM)[1]. |
分子量 | 580.49 |
Formula | C26H28O15 |
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |