包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Forigerimod TFA (IPP-201101 TFA) is aCD4T-cellmodulator. Forigerimod TFA is a 21-amino-acid fragment of U1 small nuclear ribonucleoprotein 70 kDa that is phosphorylated at Ser140. Forigerimod TFA can potently inhibitautophagy. Forigerimod can be used for the research of autoimmune disorders, such as systemic lupus erythematosus (SLE)[1][2][3][4]. | ||||||||||||||||
体内研究 (In Vivo) | Forigerimod TFA (P140) (i.v.; 100 μg in 100 μL saline per mouse) 直接作用于分子伴侣介导的自噬,使 MRL/lpr 小鼠免于唾液腺中发生的细胞浸润和自噬缺陷[4]。
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分子量 | 2752.96 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C119H182F3N34O34PS | ||||||||||||||||
Sequence Shortening | RIHMVYSKR-{Ser-phosphono}-GKPRGYAFIEY (TFA) | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 100 mg/mL(36.32 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |