Epratuzumab

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Epratuzumab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

205923-57-5

包装与价格：

产品名称

Antibody hLL 2
Anti-Human CD22 Recombinant Antibody

产品介绍

Epratuzumab (Antibody hLL 2) 是一种抗 CD22 IgG1 单克隆抗体。Epratuzumab 也是一种肿瘤显像剂和免疫调节剂。Epratuzumab 可诱导 CD22 磷酸化。Epratuzumab 已被用于研究非霍奇金淋巴瘤和一些自身免疫性疾病。

生物活性	Epratuzumab (Antibody hLL 2) is an anti-CD22IgG1monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases^[1].
体外研究 (In Vitro)	Epratuzumab binds to CD22 ECD on Biacore with a K_Dof 0.7 nM, and resulting CD22 phosphorylation^[1].Epratuzumab (0-100 μM; 1h) results in a dose dependent increase in CD22 internalization in Daudi lymphoma cells^[1].
CAS 号	205923-57-5
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.