CAS NO: | 2342597-81-1 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Garivulimab (BGB-A333) is a humanized IgG1-variant monoclonal antibody that specifically targets and binds toPD-L1. Garivulimab selectively blocks the interaction ofPD-L1andPD-1. Garivulimab has antitumor activity[1]. |
体外研究 (In Vitro) | Garivulimab (BGB-A333) specifically targets and binds to PD-L1, blocking interaction to its receptor, PD-1 on T cell, reversing T cell inactivation, and increases T cell expansion resulting in cytotoxic T cell-mediated antitumor immune response against PD-L1-expressing tumor cells. Garivulimab also inhibits PD-L1-induced apoptosis of activated CD8+ T cells and increases T cell proliferation[1]. |
CAS 号 | 2342597-81-1 |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |