CAS NO: | 10048-13-2 |
包装: | 5mg |
市场价: | 5600元 |
生物活性 | Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains fromAspergillus versicolor[1][2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects inanimals[3]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, which contributes to the induction of G2 arrest in GES-1 cells[4]. | ||||||||||||||||
体内研究 (In Vivo) | Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) inhibits p21WAF1/CIP1[3]. | ||||||||||||||||
分子量 | 324.28 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C18H12O6 | ||||||||||||||||
CAS 号 | 10048-13-2 | ||||||||||||||||
中文名称 | 甾体半胱氨酸 | ||||||||||||||||
结构分类 |
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来源 | Aspergillus versicolor | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 25 mg/mL(77.09 mM;ultrasonic and warming and heat to 80℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |