25-Hydroxycholesterol-d6 is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite ofcholesterolthat is produced and secreted by macrophages in response toToll-like receptor (TLR)activation. 25-hydroxycholesterol is a potent (EC₅₀≈65 nM) and selective suppressor ofIgAproduction by B cells^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

408.69

C₂₇H₄₀D₆O₂

88247-69-2

25-羟基胆固醇 d6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.