Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities.

Cynarin inhibits taste receptors, making water to be sweet. It has been shown to have some pharmacological properties including hypocholesterolemic, hepatoprotective, antiviral, antibacterial, and antihistamic effects. Cynarin has marked antioxidant, anticholinergic, reducing ability, radical-scavenging, and metal-binding activities. Cynarin demonstrates 87.72% inhibition of linoleic acid lipid peroxidation at 30 mg/mL concentration. Cynarin exhibits effective DMPD⁺, ABTS⁺, O₂^-, DPPH¹, and H₂O₂scavenging effects, reducing capabilities and Fe²⁺chelating effects. IC₅₀and K_iof cynarin for acetylcholinesterase enzyme inhibition are 243.67nM and 39.34±13.88 nM, respectively^[1]. Cynarin is a potential immunosuppressant that blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin blocks about 87% of the CD28-dependent "signal 2" pathway of T-cell activation under the condition of one to one ratio of T-cell and B-cell. Cynarin binds to the "G-pocket" of CD28 and thus interrupts the site of interaction between CD28 and CD80^[2].

516.45

Solid

C₂₅H₂₄O₁₂

30964-13-7

洋蓟素；洋蓟酸；菜蓟素

• Phenylpropanoids
• Other Phenylpropanoids

• Phenols
• Polyphenols

• Plants
• Compositae
• Inula japonica

Room temperature in continental US; may vary elsewhere.

DMSO : ≥ 23 mg/mL(44.53 mM)

*"≥" means soluble, but saturation unknown.

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。