Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurringantibioticfromPseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities^[1].

Safracin B (0.005-5 mg/kg/day; for 9 days) prolongs the life span of tumor-bearing mice and shows antitumor activity against L1210 and P388 leukemias and B16 melanoma in Female BALB/c x DBA/2 F₁(CD2F₁) mice weighing 19-24 g^[2].
The LD₅₀is 7.3 mg/kg with safracin B in normal CD2F₁mice by ip administration^[2].

540.61

C₂₈H₃₆N₄O₇

87578-99-2

• Quinones
• Benzene Quinones

• Phenols
• Monophenols

Pseudomonas fluorescens A2-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.