Pedaliin

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Pedaliin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

22860-72-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Pedaliin 是从芝麻 (Sesamum indicum L) 叶 (SLs) 的乙醇提取物中提取的一种生物活性成分。Pedaliin 具有体外抗氧化和抗结肠癌作用，具有自由基清除活性和铁还原抗氧化能力 (FRAP)。

生物活性

Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-coloncancerefficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP)^[1]^[2].

体外研究
(In Vitro)

Pedaliin (0-35 μM; 72 h) dose-dependently attenuates the growth of human colon cancer cells, HT29 and HCT116^[1].
Pedaliin (3.5-35 μM; 30 min; 37 ℃) has ferric reducing antioxidant power (FRAP)^[1].
Pedaliin (7 μM; 48 h) alleviates invasion and migration of HT29 and HCT116 cells in non-cytotoxic conditions^[1].
Pedaliin (20 μL) shows high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, oxygen radical absorbance capacity (ORAC), and in vitro antiglycation activities, and inhibits BSA glycation with an IC₅₀value of 41.8 μM^[2].

Cell Viability Assay^[1]

Cell Line:	HCT116 cells
Concentration:	0, 3.5, 7, 17.5, and 35 μM
Incubation Time:	48 hours or 72 hours
Result:	Inhibited cell growth (72 h) by 24% at 3.5-35 μM, invasion (48 h) by 18% at 7 μM, and migration (48 h) by 33% at 7 μM.

分子量

478.40

Formula

C₂₂H₂₂O₁₂

CAS 号

22860-72-6

结构分类

Flavonoids
Isoflavones

来源

Plants
Pedaliaceae
Sesamum indicumLinn.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.