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Cloprostenol isopropyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cloprostenol isopropyl ester图片
CAS NO:157283-66-4
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Cloprostenol isopropyl ester 是一种前列腺素 F2α 类似物,是 (+)-Cloprostenol (HY-107381) 的中间体。Cloprostenol isopropyl ester 是一种 FP 受体激动剂,其Ki值为 28 nM。
生物活性

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of(+)-Cloprostenol(HY-107381). Cloprostenol isopropyl ester is aFPreceptoragonist with aKivalue of 28 nM[1][2].

IC50& Target

FP

 

体内研究
(In Vivo)

Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis[1].
Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey[2].

Animal Model:Male mice (50–80 days)[1]
Dosage:25 μg/kg
Administration:Intraperitoneal injection; daily, for 4 weeks
Result:Stimulated the androgen synthesis in a time-dependent manner.
分子量

466.99

Formula

C25H35ClO6

CAS 号

157283-66-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.