SW2_152F is a potent, selectivechromobox 2 chromodomain (CBX2 ChD)inhibitor with aK_dof 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro^[1].

Kd: 80 nM (chromobox 2 chromodomain)^[1]

SW2_152F inhibits CBX2 chromatin binding in cells, and blocks neuroendocrine differentiation of prostate cancer cell lines in response to androgen deprivation^[1].

935.37

C₄₅H₆₂Cl₃N₇O₈

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.