CAS NO: | 154-36-9 |
包装: | 1mg |
市场价: | 1800元 |
Cas No. | 154-36-9 |
别名 | Trifoside; Prunetin 4′-O-β-D-glucopyranoside |
Canonical SMILES | O=C1C(C(OC=C1C(C=C2)=CC=C2O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)=CC(OC)=C4)=C4O |
分子式 | C22H22O10 |
分子量 | 446.4 |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2]. Prunetin inhibits LPS-induced nitric oxide and prostaglandin E2 production through the suppression of iNOS and COX-2 at the transcriptional level[1].Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells[2]. [1]. Yang G, et al. Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway. Food Chem Toxicol. 2013;58:124-132. [2]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018;106:1469-1477. |