您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Doxorubicin-13C,3d TFA
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Doxorubicin-13C,3d TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Doxorubicin-13C,3d TFA图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
Hydroxydaunorubicin-13C,3d TFA
产品介绍
Doxorubicin-13C,3d TFA 是 13C 标记的 Doxorubicin 的氘代物。 Doxorubicin (Hydroxydaunorubicin) 是一种有细胞毒性的蒽环类抗生素,常用作肿瘤化疗剂。Doxorubicin 抑制拓扑异构酶 II (topoisomerase-II),IC50为 2.67 μM,从而抑制 DNA 复制。Doxorubicin 下调AMPK的基础磷酸化以及下游 acetyl-CoA 羧化
生物活性

Doxorubicin-13C,3d TFA is the deuterium and 13C labeled Doxorubicin. Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracyclineantibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibitstopoisomeraseII with an IC50 of 2.67 μM, thus stoppin

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

661.55

Formula

C2813CH27D3F3NO13

中文名称

阿霉素 13C,3d;多柔比星 13C,3d

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.