| CAS NO: | 135304-07-3 |
| 包装: | 5mg (27.2 mM * 500 μL in Methyl acetate) |
| 市场价: | 3700元 |
| 生物活性 | Arazine (N-Acetyl-S-farnesyl-L-cysteine) is a cell-permeable modulator ofG protein and G-protein coupled receptorsignaling. Arazine can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site[1]. | ||||||||
| 体外研究 (In Vitro) | Arazine (2 hours) inhibits ATPγS induced CXCL1, CXCL8 and CCL2 production as a dose-dependent manner in HMEC-1 cell[1].Arazine (10–100 μM;8 hours) significantly affects the HMEC-1 cell viability as measured by trypan blue exclusion in HMEC-1 cell[1]. | ||||||||
| 体内研究 (In Vivo) | Arazine (AFC) (2,000 μg/20 μl; applied on ear) produces a dose-dependent inhibition of the TPA-induced edema, with the maximal reduction of edema approaching 73%, with a 50% effective dose (ED50) of 55±12 μg/20 μl[1].
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| 分子量 | 367.55 | ||||||||
| 性状 | Liquid | ||||||||
| Formula | C20H33NO3S | ||||||||
| CAS 号 | 135304-07-3 | ||||||||
| 中文名称 | N-乙酰基-S-法呢基-L-半胱氨酸 | ||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 | Solution, -20°C, 2 years |
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