2'-C-Methyladenosine

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CAS NO:

15397-12-3

包装与价格：

包装	价格(元)
50mg	电议
100mg	电议

产品介绍

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM.

Cas No.	15397-12-3
别名	2'-C-甲基腺苷
Canonical SMILES	NC1=NC=NC2=C1N=CN2[C@H]3[C@@](O)(C)[C@H](O)[C@@H](CO)O3
分子式	C₁₁H₁₅N₅O₄
分子量	281.3
溶解度	DMF: 5 mg/mL,DMSO: 20 mg/mL,PBS (pH 7.2): 10 mg/mL
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 µM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 µM. It is converted intracellularly to adenosine triphosphate, which inhibits the RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). It also inhibits growth of L. guyanensis in vitro (EC50 = 3 µM) and eradicates it when used at a concentration of 10 µM.