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LSD1/ER-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LSD1/ER-IN-1图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
LSD1/ER-IN-1 (compound 11g) 是一种有效的ERLSD1抑制剂,其IC50为 1.55 μM (LSD1)。LSD1/ER-IN-1 对ERα蛋白有高亲和力选择性,α/β 比为7.11。LSD1/ER-IN-1 对 MCF-7 乳腺癌细胞具有良好的抗增殖活性,其IC50为8.79 μM。
生物活性

LSD1/ER-IN-1 (compound 11g) is a potentERandLSD1inhibitor, with anIC50of 1.55 μM (LSD1). LSD1/ER-IN-1 has high affinity selectivity forERαprotein, with α/β ratio of 7.11. LSD1/ER-IN-1 shows good antiproliferative activity against MCF-7 breastcancercells, with anIC50of 8.79 μM[1].

IC50& Target

ERα

 

ERβ

 

体外研究
(In Vitro)

LSD1/ER-IN-1 (compound 11g) (0-30 μM, 24 h) induces apoptosis in MCF-7 cells in a dose-dependent manner[1].

分子量

455.46

Formula

C23H18FNO6S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.