您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Bromelain
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Bromelain
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:9001-00-7
包装与价格:
包装价格(元)
100mg电议
200mg电议
500mg电议

产品名称
菠萝蛋白酶
产品介绍
Bromelain 是一种源自菠萝茎的抗炎药,其通过下调血浆激肽原,抑制前列腺素 E2 表达,降解晚期糖基化终产物受体,调节血管生成生物标志物以及在COX途径上游发生抗氧化作用而发挥作用。Bromelain 具有多种纤维蛋白溶解,抗水肿,抗血栓形成和抗炎活性。Bromelain 还具有一些抗癌活性,并促进凋亡细胞死亡。
生物活性

Bromelain is an anti-inflammatory drug derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition ofProstaglandin E2expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in theCOX-pathway[1]. Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotesapoptoticcell death[2].

体内研究
(In Vivo)

Bromelain (40 mg/kg; intraperitoneal injection; daily; for 7 days; male Sprague-Dawley rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD). 6-OHDA injection resulted in marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion[1].

Animal Model:Male Sprague-Dawley rats injected with 6-OHDA[1]
Dosage:40 mg/kg
Administration:Intraperitoneal injection; daily; for 7 days
Result:Reduced the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD).
Clinical Trial
性状

Solid

CAS 号

9001-00-7

中文名称

菠萝蛋白酶;鳳梨酶;菠萝酶;鳳梨酵素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month