CAS NO: | 1352792-74-5 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
Molecular Weight (MW) | 348.42 |
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Formula | C20H16N2O2S |
CAS No. | 1352792-74-5 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: ≥ 30mg/mL |
Water: N/A | |
Ethanol: N/A | |
Chemical Name | 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid |
Synonyms | RDEA-3170; RDEA3170; RDEA 3170 |
SMILES Code | CC(C)(SC1=C(C2=C3C=CC=CC3=C(C#N)C=C2)C=NC=C1)C(O)=O |
Target |
IC50: 25 nM (URAT1)[1] |
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In Vitro | Verinurad inhibits the transportation activity of human URAT1 in a dose-dependent manner with an IC50 of 25 nM [1]. |
References |
[1]. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7(1):665 |