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(Pro3)GIP,human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:299898-52-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
(Pro3) Gastric Inhibitory Peptide, human
产品介绍
(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) 是一种有效、稳定和特异性的人 GIP 受体完全激动剂。(Pro3) GIP, human 对人 GIPR 具有高结合亲和力,Ki/ Kd值为 0.90 nM。(Pro3) GIP, human可用于肥胖相关糖尿病的研究。
生物活性

(Pro3) GIP, human ((Pro3)Gastric Inhibitory Peptide, human) is an efficacious, stable and specifichuman GIP receptor (hGIPR)full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with Ki/ Kdvalues of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes[1][2].

IC50& Target

EC50: 0.026 nM (hGIPR)[2]
Ki/Kd: 0.90 nM (hGIPR); 1.1 nM (Rat GIPR); 0.72 nM (Mouse GIPR)[2]

体外研究
(In Vitro)

(Pro3) GIP, human induces cAMP accumulation with an EC50value of 0.026 nM[2].
(Pro3) GIP, human has high binding affinity for human GIPR, Rat GIPR and Mouse GIPR with Ki/ Kdvalues of 0.90 nM, 1.1 nM and 0.72 nM, respectively[2].

体内研究
(In Vivo)

(Pro3) GIP, human has comparatively weak partial agonist effect in rodent models[2].

分子量

4951.53

Formula

C226H338N60O64S

CAS 号

299898-52-5

Sequence Shortening

YAPGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.