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GIP(1-30)amide,human
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:198624-01-0
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
GIP (1-30) amide,human 是葡萄糖依赖性促胰岛素多肽 (GIP) 片段。葡萄糖依赖性促胰岛素多肽是一种肠降血糖素激素,可刺激胰岛素分泌并减少餐后血糖波动。GIP (1-30) amide,human 在 10-9-10-6M 范围内剂量依赖性地促进胰岛素分泌。
生物活性

GIP (1-30) amide,human is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulatesinsulinsecretion and reduces postprandial glycaemic excursions. GIP (1-30) amide,human dose-dependently promotesinsulinsecretion over the range 10-9-10-6M[1].

体外研究
(In Vitro)

The glucose-dependent action of Glucose-dependent insulinotropic polypeptide (GIP) on pancreatic β-cells has attracted attention towards its exploitation as a potential drug for type 2 diabetes. In a 50% aqueous trifluoroethanol solvent, GIP(1-30) amide has an α-helical structural region from F6 to A28. The structures calculated for GIP(1-30) amide remain within one family of conformations and the level of agreement between the structures demonstrated the ordered arrangement[1].

分子量

3531.94

Formula

C162H240N40O47S

CAS 号

198624-01-0

Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-NH2

Sequence Shortening

YAEGTFISDYSIAMDKIHQQDFVNWLLAQK-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.