| CAS NO: | 66592-87-8 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| Cas No. | 66592-87-8 |
| 别名 | 头孢羟氨苄一水合物; BL-S 578 hydrate |
| 化学名 | (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monohydrate |
| Canonical SMILES | OC1=CC=C([C@@H](N)C(N[C@@H]2C(N3[C@]2([H])SCC(C)=C3C(O)=O)=O)=O)C=C1.O |
| 分子式 | C16H17N3O5S o H2O |
| 分子量 | 381.4 |
| 溶解度 | ≥ 5.8mg/mL in DMSO with gentle warming |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cefadroxil is a new semisynthetic cephalosporin with a broad antibacterial spectrum and a high chemotherapeutic potential [1]. In vitro: The inhibitory activity of this compound was similar to that of cephalexin and cephradine when tested against 602 clinical isolates on Mueller-Hinton medium. In the oral treatment of experimental infections of mice, cefadroxil was more effective than cephalexin against Streptococcus pyogenes, and comparably effective against Streptococcus pneumoniae, Staphylococcus aureus, and several gram-negative species [1]. In vivo: In mice, oral administration of cefadroxil at doses ranging from 25 to 100 mg/kg attained peak concentrations in the blood. Higher peak levels were noted with cefadroxil than with cephalexin at a dose of 200 mg/kg [1]. Clinical trials: A single daily dose of cefadroxil appeared to be as effective in the treatment of patients with A β-hemolytic streptococcal (GABHS) pharyngitis [2]. References: |
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