Pazopanib-d6 (GW786034-d6) is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor ofVEGFR1,VEGFR2,VEGFR3,PDGFRβ,c-Kit,FGFR1, andc-FmswithIC₅₀s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

443.55

C₂₁H₁₇D₆N₇O₂S

1219592-01-4

帕唑帕尼 d6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.