黄柏碱是一种在黄柏中发现的植物生物碱。 Phellodendrine chloride 通过抑制巨胞饮作用对营养物质的摄取来抑制 KRAS 突变的胰腺癌细胞的增殖。黄柏碱通过调节 AMPK/mTOR 通路促进自噬，减少溃疡性结肠炎的肠道损伤。
| Cas No. | 104112-82-5 |
| 别名 | 盐酸黄柏碱 |
| 化学名 | (13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol;chloride |
| Canonical SMILES | C[N+]12CCC3=CC(=C(C=C3C1CC4=CC(=C(C=C4C2)OC)O)O)OC.[Cl-] |
| 分子式 | C20H24NO4Cl |
| 分子量 | 377.85 |
| 溶解度 | ≥ 18.9mg/mL in DMSO with ultrasonic and warming |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Extracted from PhellodendronchineseSchneid. dried barks;Store the product in sealed, cool and dry condition |
m.cnreagent.com