Methyltetrazine-PEG5-alkyne is a PEG-basedPROTAClinker that can be used in the synthesis ofPROTACs^[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

402.44

Solid

C₂₀H₂₆N₄O₅

1802907-97-6

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)