PG 106 是一种有效的选择性人黑皮质素 3 (hMC3) 受体拮抗剂 (IC50\u003d210 nM)，对 hMC4 受体 (EC50\u003d9900 nM) 和 hMC5 受体没有活性。
| Cas No. | 944111-22-2 |
| 化学名 | (1Z,3S,4Z,6S,7Z,9R,10Z,14Z,16S,18Z,24S)-3-((1H-indol-3-yl)methyl)-6-(3-guanidinopropyl)-2,5,8,11,15,18-hexahydroxy-16-((Z)-(1-hydroxy-2-((Z)-(1-hydroxyethylidene)amino)hexylidene)amino)-9-(naphthalen-2-ylmethyl)-1,4,7,10,14,19-hexaazacyclotetracosa-1,4,7, |
| Canonical SMILES | CCCCC(/N=C(O)/C)([H])/C(O)=N/[C@@](/C(O)=N/CC/C(O)=N/[C@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/1)([H])CC2=CNC3=CC=CC=C23)([H])CCCNC(N)=N)([H])CC4=CC5=CC=CC=C5C=C4)([H])C/C(O)=N/CCCC[C@@]1([H])C(O)=N |
| 分子式 | C51H69N13O9 |
| 分子量 | 1008.19 |
| 溶解度 | Soluble to 1 mg/ml in 25% ethanol / Water |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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