Thiol-PEG2-t-butyl ester is a PEG-basedPROTAClinker that can be used in the synthesis ofPROTACs^[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

250.35

C₁₁H₂₂O₄S

1398044-50-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.